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A ‘Game Changer’ For Organ Transplants: Blood Type of Donor Kidneys Altered in Breakthrough Research_我的网站

一 |     Breakthrough new research could significantly increase supply of organs for people with rarer blood types waiting for a transplant, reported The Guardian.,A team of scientists from the University of Cambridge have successfully altered the blood type of three donor kidneys. By flushing blood infused with a special enzyme through a human kidney the scientists removed the blood type markers lining the blood vessels of the organ.,The procedure required using a device that is connected with a donor’s kidney to pass oxygenated blood through it - a normothermic perfusion machine. As a result, the organ was converted to type O, considered the universal donor.,Blood Group Compatible,As the blood type of a donor must be compatible with the recipient’s, the new development could increase the supply of kidneys available for transplant.,A kidney from someone with blood type A cannot be transplanted to someone with blood type B, or visa versa. In such a case, the receiving body’s immune system would reject the new organ, interpreting the different blood type as foreign.,So changing the blood type to the universal O would mean the donor organ could be used for people with any blood type.,“Our confidence was really boosted after we applied the enzyme to a piece of human kidney tissue and saw very quickly that the antigens were removed. After this, we knew that the process is feasible, and we just had to scale up the project to apply the enzyme to full-size human kidneys,” Serena MacMillan, a PhD student at the University of Cambridge, said.,Scientists involved in the research, funded by charity Kidney Research UK and due to be published in the British Journal of Surgery, clarified that the outcome might have particular implications for minority ethnic groups.,Science & TechGood News for ABs: Scientists Can Now Change People's Blood Type21 February, 16:34 GMT,Some blood groups such as O Rh positive and B Rh positive are more prevalent among black, Asian and minority ethnic communities. To complicate matters further, some rare blood types are only found within the black, Asian and minority ethnic communities,This typically places them at a disadvantage, as they struggle to find a match. With low donation rates from these populations, stressed the researchers, sometimes such patients wait for as long as over a year for a compatible donor. They cited figures from 2020-21 showing that just over 9% of total organ donations in the UK came from black and minority ethnic donors. On the other hand, black and minority ethnic patients make up 33% of the kidney transplant waiting list.,“It’s very exciting to think about how this could potentially impact so many lives,” added Serena MacMillan.,The “potentially gamechanging” research was applauded by Dr Aisling McMahon, the executive director of research at Kidney Research UK.,The scientists will now test the reintroduction of other blood types and observe how the novel approach in clinical settings.。    08月26日讯 勒沃库森中场马扎近日接受《体育图片报》的采访，谈到了今年夏天他代表阿尔及利亚参加世界杯的经历，特别是第一场与阿根廷的比赛。你的世界杯之旅感觉如何？你代表阿尔及利亚队首发出战了全部四场比赛。

二 | 马扎：世界杯是世界上规模最大的赛事。能够参赛并踢完四场比赛简直太棒了，你永远不会忘记这样的经历。阿尔及利亚世界杯首战0-3负于阿根廷，梅西包办了全部三个进球。你对梅西的印象如何？马扎：这太疯狂了，因为我一直梦想着能和梅西以及C罗交手，我已经和其中一位交过手了。作为一名年轻球员，能有这样的经历是一种荣幸。但这并没有阻止我在比赛中全力以赴，我尽了自己的一份力，开场几分钟就差点送出一次助攻。最终我们还是没能赢球，在面对卫冕冠军和最终的亚军阿根廷时，这很正常。梅西不仅因为进球而备受关注，还因为对阿尔及利亚队长艾沙·曼迪的一次鲁莽犯规而引起热议。他是否应该因此被红牌罚下？马扎：我当时的位置离事发地很远，和很多队友一样，并没有真正看到具体情况。除了艾沙之外，没有人提出抗议。也许梅西当时有点幸运，但裁判已经做出了判罚，事情就此结束。

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